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Additionally, biomechanical loading modulates ROS generation via integrin mechanotransduction and calcium influx, which in turn influences ROS-dependent gene expression through mechano-sensitive pathways like YAP/TAZ and MAPK/ERK (Xu Z

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Natural bioactive compounds such as retinoids, peptides and antioxidants (such as vitamin C) and PCs play beneficial roles in the prevention and treatment of skin aging